THOMAS A. PUGSLEY: search on Z-Library

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1

Cardiorespiratory safety evaluation in non-human primates

Jennifer L. Ingram-Ross, Aidan K. Curran, Mutsumi Miyamoto, Jennifer Sheehan, Gareth Thomas, Johan Verbeeck, Eric J. de Waal, Birgit Verstynen, Michael K. Pugsley

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2012

Language:

english

File:

PDF, 5.32 MB

english, 2012

2

2-(2-Aryl-2-oxoethylidene)-1,2,3,4-tetrahydropyridines. Novel isomers of 1,4-dihydropyridine calcium channel blockers

Taylor, Michael D., Badger, Edward W., Steffen, Robert P., Haleen, Stephen J., Pugsley, Thomas A., Shih, Yu Hsin, Weishaar, Ronald E.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 900 KB

english, 1988

3

Affinity for Dopamine D 2 , D 3 , and D 4 Receptors of 2-Aminotetralins. Relevance of D 2 Agonist Binding for Determination of Receptor Subtype Selectivity †

van Vliet, L. Alexander, Tepper, Pieter G., Dijkstra, Durk, Damsma, Geert, Wikström, Håkan, Pugsley, Thomas A., Akunne, Hyacinth C., Heffner, Thomas G., Glase, Shelly A., Wise, Lawrence D.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 136 KB

english, 1996

4

Reactor Grids for Prioritizing Syphilis Investigations

Cha, Susan, Matthias, James M., Rahman, Mohammad, Schillinger, Julia A., Furness, Bruce W., Pugsley, River A., Kidd, Sarah, Bernstein, Kyle T., Peterman, Thomas A.

Journal:

Sexually Transmitted Diseases

Year:

2018

Language:

english

File:

PDF, 2.01 MB

english, 2018

5

Structure-activity and conformational studies of a series of modified C-terminal hexapeptide neurotensin analogues

DEBORAH L. HEYL, NDREA M. SEFLER, JOHN X. HE, TOMI K. SAWYER, DAVID J. WUSTROW, HYACINTH C. AKUNNE, M. DUFF DAVIS, THOMAS A. PUGSLEY, THOMAS G. HEFFNER, ANN E. CORBIN, WAYNE L. CODY

Journal:

Chemical Biology & Drug Design

Year:

1994

Language:

english

File:

PDF, 559 KB

english, 1994

6

Characterization of binding of [3H]PD 128907, A selective Dopamine D3 receptor agonist ligand, to CHO-K1 cells

Hyacinth C. Akunne, Patrick Towers, Gareth J. Ellis, Durk Dijkstra, Håkan Wikström, Thomas G. Heffner, Lawrence D. Wise, Thomas A. Pugsley

Journal:

Year:

1995

Language:

english

File:

PDF, 772 KB

english, 1995

7

Decrease in rat straital dopamine synthesis and metabolism in vivo by metabolically stable adenosine receptor agonists

Sharie Myers, Thomas A. Pugsley

Journal:

Year:

1986

Language:

english

File:

PDF, 376 KB

english, 1986

8

Binding of leukotrienes C4 and D4 to membranes from guinea pig lung: Regulation by ions and gaunine nucleotides

Robert F. Bruns, William J. Thomsen, Thomas A. Pugsley

Journal:

Year:

1983

Language:

english

File:

PDF, 403 KB

english, 1983

9

Dopamine autoreceptor agonists as potential antipsychotics. 2. (Aminoalkoxy)-4H-1-benzopyran-4-ones

Jaen, Juan C., Wise, Lawrence D., Heffner, Thomas G., Pugsley, Thomas A., Meltzer, Leonard T.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 1.13 MB

english, 1991

10

DISCUSSION. CONCEPTS OF SAFETY IN STRUCTURAL ENGINEERING.

PUGSLEY, A G, CLANVILLE, W H, BAKER, A A L, THOMAS, F G, TYE, W, HORNE, M R, O SULLIVAN, T P, ROOKE, G W, HAJNAL KONYI, K, SIMPSON, N G, NORTH, J D, WALKER, P B

Journal:

Journal of the ICE

Year:

1951

Language:

english

File:

PDF, 1.24 MB

english, 1951

11

Selective inhibition of the cyclooxygenase pathway of the arachidonic acid cascade by the nonsteroidal antiinflammatory drug isoxicam

Dr. Thomas A. Pugsley, Carolyn Spencer, Amal M. Boctor, Melvyn I. Gluckman

Journal:

Drug Development Research

Year:

1985

Language:

english

File:

PDF, 465 KB

english, 1985

12

Synthesis and Pharmacology of Benzoxazines as Highly Selective Antagonists at M 4 Muscarinic Receptors.

Böhme, Thomas M., Augelli-Szafran, Corinne E., Hallak, Hussein, Pugsley, Thomas, Serpa, Kevin, Schwarz, Roy D.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 18 KB

english, 2002

13

Chromeno[3,4- c ]pyridin-5-ones: Selective Human Dopamine D 4 Receptor Antagonists as Potential Antipsychotic Agents

Unangst, Paul C., Capiris, Thomas, Connor, David T., Heffner, Thomas G., MacKenzie, Robert G., Miller, Steven R., Pugsley, Thomas A., Wise, Lawrence D.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 169 KB

english, 1997

14

Effects of CI-926 (3-[4-[4-(3-Methylphenyl)-l-Piperazinyl] Butyl]-2,-4-Imidazolidinedione), an Antihypertensive Agent, on Rat Brain Catecholamine and Serotonin Turnover

Pugsley, Thomas A., Myers, Sharie M., Shih, Yu-Hsin

Journal:

Journal of Cardiovascular Pharmacology

Year:

1989

File:

PDF, 724 KB

1989

15

Some neurochemical properties of pramiracetam (CI-879), a new cognition-enhancing agent

Dr. Thomas A. Pugsley, Yu-Hsin Shih, Linda Coughenour, Sheila F. Stewart

Journal:

Drug Development Research

Year:

1983

Language:

english

File:

PDF, 957 KB

english, 1983

16

(5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)methanones. A series of novel potential antipsychotic agents

Wise, Lawrence D., Butler, Donald E., DeWald, Horace A., Lustgarten, David, Coughenour, Linda L., Downs, David A., Heffner, Thomas G., Pugsley, Thomas A.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 1.23 MB

english, 1986

17

Synthesis and potential antipsychotic activity of 1H-imidazo[1,2-c]pyrazolo[3,4-e]pyrimidines

DeWald, Horace A., Beeson, Nicholas W., Hershenson, Fred M., Wise, Lawrence D., Downs, David A., Heffner, Thomas G., Coughenour, Linda L., Pugsley, Thomas A.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 1.07 MB

english, 1988

18

1,3-Dialkyl-4-(iminoarylmethyl)-1H-pyrazol-5-ols. A series of novel potential antipsychotic agents

Wise, Lawrence D., Butler, Donald E., DeWald, Horace A., Lustgarten, David M., Pattison, Ian C., Schweiss, Dieter N., Coughenour, Linda L., Downs, David A., Heffner, Thomas G., Pugsley, Thomas A.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 798 KB

english, 1987

19

Novel 4,5,6,7-tetrahydrobenzothiazole dopamine agonists display very low stereoselectivity in their interaction with dopamine receptors.

Juan C. Jaen, Bradley W. Caprathe, Lawrence D. Wise, Sarah J. Smith, Thomas A. Pugsley, Thomas G. Heffner, Leonard T. Meltzer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1991

Language:

english

File:

PDF, 270 KB

english, 1991

20

Synthesis and Pharmacological Evaluation of Thiopyran Analogues of the Dopamine D3 Receptor-Selective Agonist (4aR,10bR)-(+)-trans-3,4,4a,10b- Tetrahydro-4-n-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol (PD 128907)

van Vliet, L. Alexander, Rodenhuis, Nienke, Dijkstra, Durk, Wikström, Håkan, Pugsley, Thomas A., Serpa, Kevin A., Meltzer, Leonard T., Heffner, Thomas G., Wise, Lawrence D., Lajiness, Mary E.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 367 KB

english, 2000

21

Effect of clofibrate on biogenic amine levels and turnover

Thomas Pugsley, Wilbur Lippmann

Journal:

Pharmacological Research Communications

Year:

1976

Language:

english

File:

PDF, 478 KB

english, 1976

22

Kirk-Othmer Encyclopedia of Chemical Technology || Epinephrine and Norepinephrine

Pugsley, Thomas A.

Year:

2000

Language:

english

File:

PDF, 188 KB

english, 2000

23

Presumptive and Follow-up Treatment for Gonorrhea and Chlamydia Among Patients Attending Public Health Department Clinics in Virginia, 2016

Pugsley, River A., Peterman, Thomas A.

Journal:

Sexually Transmitted Diseases

Year:

2019

File:

PDF, 152 KB

2019

24

4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines: a novel class of compounds with central dopamine agonist properties

Jaen, Juan C., Wise, Lawrence D., Caprathe, Bradley W., Tecle, Haile, Bergmeier, Stephen, Humblet, Christine C., Heffner, Thomas G., Meltzer, Leonard T., Pugsley, Thomas A.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 1002 KB

english, 1990

25

Identification, Characterization and Pharmacological Profile of Three Metabolites of (R)-(+)-1,2,3,6-Tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1-yl)methyl]p yridine (CI-1007), a Dopamine Autoreceptor Agonist and Potential Antipsychotic Agent

Wright, Jon L., Downing, Dennis M., Feng, M. Rose, Hayes, Roger N., Heffner, Thomas G., MacKenzie, Robert G., Meltzer, Leonard T., Pugsley, Thomas A., Wise, Lawrence D.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 927 KB

english, 1995

26

Cell regulation: continually redefining the rules

Anthony P Pugsley, Thomas J Silhavy

Journal:

Current Opinion in Microbiology

Year:

1998

Language:

english

File:

PDF, 353 KB

english, 1998

27

A Series of 6- and 7-Piperazinyl- and -Piperidinylmethylbenzoxazinones with Dopamine D4 Antagonist Activity: Discovery of a Potential Atypical Antipsychotic Agent

Belliotti, Thomas R., Wustrow, David J., Brink, Wouter A., Zoski, Kim T., Shih, Yu-Hsin, Whetzel, Steven Z., Georgic, Lynn M., Corbin, Ann E., Akunne, Hyacinth C., Heffner, Thomas G., Pugsley, Thomas

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 106 KB

english, 1999

28

EARLY RENAL TRANSPLANT OUTCOMES IN AUSTRALIAN ABORIGINES

Thomas Mc, Juneja R, Mathew Th, Russ Gr, Rao M Mohan, Disney Aps, Pugsley Ds, Martin G

Journal:

Year:

2002

Language:

english

File:

PDF, 381 KB

english, 2002

29

Theophylline and Salbutamol Improve Pulmonary Function in Patients with Irreversible Chronic Obstructive Pulmonary Disease

Thomas, Peter, Pugsley, John A., Stewart, John H.

Journal:

Year:

1992

Language:

english

File:

PDF, 1.31 MB

english, 1992

30

Synthesis and pharmacological evaluation of the enantiomers of the dopamine autoreceptor agonist PD 135385

Juan C. Jaén, Bradley W. Caprathe, Lawrence D. Wise, Leonard T. Meltzer, Thomas A. Pugsley, Thomas G. Huffner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 457 KB

english, 1993

31

The effects of tandamine, a new potential antidepressant agent, on biogenic amine uptake mechanisms and related activities

Wilbur Lippmann, Thomas A. Pugsley

Journal:

Biochemical Pharmacology

Year:

1976

Language:

english

File:

PDF, 663 KB

english, 1976

32

A New Type of Prodrug of Catecholamines: An Opportunity To Improve the Treatment of Parkinson's Disease

Venhuis, Bastiaan J., Rodenhuis, Nienke, Wikström, Håkan V., Wustrow, David, Meltzer, Leonard T., Wise, Lawrence D., Johnson, Stephen J., Pugsley, Thomas A., Sundell, Staffan, Dijkstra, Durk

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 14 KB

english, 2002

33

Synthesis and dopamine agonist properties of (+)-trans-3,4,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol and its enantiomers

DeWald, Horace A., Heffner, Thomas G., Jaen, Juan C., Lustgarten, David M., McPhail, Andrew T., Meltzer, Leonard T., Pugsley, Thomas A., Wise, Lawrence D.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 897 KB

english, 1990

34

Discrimination of Anterograde From Retrograde Atrial Electrograms for Physiologic Pacing

GERALD C. TIMMIS, DOUGLAS C. WESTVEER, DONOVAN M. BAKALYAR, THOMAS J. PUGSLEY, JAMES R. STEWART, SEYMOUR GORDON

Journal:

Pacing and Clinical Electrophysiology

Year:

1988

Language:

english

File:

PDF, 702 KB

english, 1988

35

Agonist properties of a stable hexapeptide analog of neurotensin, NαMeArg-Lys-Pro-Trp-tLeu-Leu (NT1)

Hyacinth C. Akunne, Steven B. Demattos, Steven Z. Whetzel, David J. Wustrow, Duff M. Davis, Lawrence D. Wise, Wayne L. Cody, Thomas A. Pugsley, Thomas G. Heffner

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 1013 KB

english, 1995

36

Aryl 1-But-3-ynyl-4-phenyl-1,2,3,6-tetrahydropyridines as Potential Antipsychotic Agents: Synthesis and Structure−Activity Relationships

Glase, Shelly A., Akunne, Hyacinth C., Heffner, Thomas G., Jaen, Juan C., MacKenzie, Robert G., Meltzer, Leonard T., Pugsley, Thomas A., Smith, Sarah J., Wise, Lawrence D.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 304 KB

english, 1996

37

Substituted [(4-Phenylpiperazinyl)- methyl]benzamides: Selective Dopamine D 4 Agonists

Glase, Shelly A., Akunne, Hyacinth C., Georgic, Lynn M., Heffner, Thomas G., MacKenzie, Robert G., Manley, Peter J., Pugsley, Thomas A., Wise, Lawrence D.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 81 KB

english, 1997

38

Efficacy of Ciprofloxacin in the Treatment of Nasopharyngeal Carriers of Neisseria meningitidis

Mary P. Pugsley, David L. Dworzack, Edward A. Horowitz, Thomas A. Cuevas, W. Eugene Sanders Jr. and Christine C. Sanders

Journal:

The Journal of Infectious Diseases

Year:

1987

Language:

english

File:

PDF, 653 KB

english, 1987

39

Synthesis and dopaminergic activity of the enantiomers of 6-methyl-4,5a,6,7,8-hexahydrothiazolo[4,5-f]quinolin-2-amine (PD 128483).

Juan C. Jaen, Bradley W. Caprathe, Lawrence D. Wise, Thomas A. Pugsley, Leonard T. Meltzer, Thomas G. Heffner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1991

Language:

english

File:

PDF, 428 KB

english, 1991

40

Synthesis and antihypertensive activity of some thienylethanolamines

Bagli, Jehan F., Mackay, Walter D., Ferdinandi, Eckhardt, Cayen, Mitchell N., Vavra, Ivan, Pugsley, Thomas, Lippmann, Wilbur

Journal:

Journal of Medicinal Chemistry

Year:

1976

Language:

english

File:

PDF, 928 KB

english, 1976

41

Pseudallescheria boydii Brain Abscess

Dworzack, David L., Clark, Richard B., Borkowski, Winslow J., Smith, David L., Dykstra, Mark, Pugsley, Mary P., Horowitz, Edward A., Connolly, Thomas L., McKinney, Daniel L., Hostetler, Marcia K., Fit

Journal:

Medicine (Williams & Wilkins)

Year:

1989

File:

PDF, 637 KB

1989

42

Fibrin Degradation Products in Pre-eclamptic Toxaemia and Eclampsia

Henderson, A. H., Pugsley, D. J., Thomas, D. P.

Journal:

Year:

1970

Language:

english

File:

PDF, 741 KB

english, 1970

43

Synthesis and dopaminergic activity of pyridine analogs of 5-hydroxy-2-(di-n-propylamino)tetralin

Glase, Shelly A., Corbin, Ann E., Pugsley, Thomas A., Heffner, Thomas G., Wise, Lawrence D.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 746 KB

english, 1995

44

Synthesis and Pharmacology of Benzoxazines as Highly Selective Antagonists at M 4 Muscarinic Receptors

Böhme, Thomas M., Augelli-Szafran, Corinne E., Hallak, Hussein, Pugsley, Thomas, Serpa, Kevin, Schwarz, Roy D.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 116 KB

english, 2002

45

4-Aryltetrahydropyridines as selective σ ligands

David J. Wustrow, Lawrence D. Wise, Thomas A. Pugsley, Leonard T. Meltzer, Thomas G. Heffner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 251 KB

english, 1993

46

[BMJ Publishing Group Ltd Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14â17, 2019, Vancouver, Canada - ()] Poster Presentations - P737âEvaluating syphilis partner notification outcomes in seven jurisdictions

Cope, Anna, Matthias, James, Rahman, Mohammad, Diesel, Jill, Pugsley, River, Schillinger, Julia, Ng, Rilene, Klingler, Ellen, Mobley, Victoria, Samoff, Erika, Bernstein, Kyle, Peterman, Thomas

File:

PDF, 85 KB

47

Thiazoloindans and Thiazolobenzopyrans: A Novel Class of Orally Active Central Dopamine (Partial) Agonists

van Vliet, L. Alexander, Rodenhuis, Nienke, Wikström, Håkan, Pugsley, Thomas A., Serpa, Kevin A., Meltzer, Leonard T., Heffner, Thomas G., Wise, Lawrence D., Lajiness, Mary E., Huff, Rita M., Svensson

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 163 KB

english, 2000

48

Two-Dimensional Reaction Engineering Model of the Riser Section of a Fluid Catalytic Cracking Unit

Berry, Thomas A., McKeen, Timothy R., Pugsley, Todd S., Dalai, Ajay K.

Journal:

Industrial & Engineering Chemistry Research

Year:

2004

Language:

english

File:

PDF, 139 KB

english, 2004

49

Evaluation of the effects of the enantiomers of reduced haloperidol, azaperol, and related 4-amino-1-arylbutanols on dopamine and .sigma. receptors

Jaen, Juan C., Caprathe, Bradley W., Pugsley, Thomas A., Wise, Lawrence D., Akunne, Hyacinth

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.07 MB

english, 1993

50

3-[[(4-Aryl-1-piperazinyl)alkyl]cyclohexyl]-1 H -indoles as Dopamine D2 Partial Agonists and Autoreceptor Agonists

Wustrow, David J., Smith, William J., Corbin, Ann E., Davis, M. Duff, Georgic, Lynn M., Pugsley, Thomas A., Whetzel, Steven Z., Heffner, Thomas G., Wise, Lawrence D.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 265 KB

english, 1997

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